Stephen C. Kolwicz Jr.

DepartmentHealth Sciences

DegreesB.S., Rutgers University-Camden M.S., East Stroudsburg University Ph.D., Temple University Postdoctoral Training NMR Laboratory for Physiological Chemistry, Brigham and Women's Hospital, Harvard Medical School Mitochondria & Metabolism Center, University of Washington TeachingStructural Kinesiology
Structural Kinesiology Lab
Exercise Physiology
Exercise Physiology Lab
Clinical Exercise Physiology
Research Methods in Health and Human Performance
Nutrition
Common Intellectual Experience (CIE)


Research Interests Dr. Kolwicz has a long-standing interest in the role of lipid metabolism in the development of cardiac dysfunction.  His past work, using genetic approaches, revealed a potential of enhanced cardiac lipid metabolism to protect the heart from acute and chronic stressors.  Current and future work will investigate the metabolic adaptations that occur in both cardiac and skeletal muscle during acute and chronic exercise training.
Recent WorkPublications:
Selected publications:
O'Neill CC, Locke EJ, Sipf DA, Thompson JH, Drebushenko EK, Berger NS, Segich BS, Kolwicz SC Jr. The Effects of Exercise Training on Glucose Homeostasis and Muscle Metabolism in Type 1 Diabetic Female Mice. Metabolites. 2022 Oct 5;12(10):948. doi: 10.3390/metabo******** . PMID: ********
Holcomb, L.E., Rowe, P., O'Neill, C.C., DeWitt, E.A.,Kolwicz Jr., S.C. Sex differences in endurance exercise capacity and skeletal muscle lipid metabolism in mice. Physiological Reports, 10(3):e15174, 2022. doi: 10.14814/phy2.15174. PMID: ********
Kolwicz Jr., S.C. Ketone Body Metabolism in the Ischemic Heart. Frontiers in Cardiovascular Medicine, 8: 789458, 2021. doi: 10.3389/fcvm.2021.789458. PMID: ********
Holcomb LE, O'Neill CC, DeWitt EA, Kolwicz SC Jr. The Effects of Fasting or Ketogenic Diet on Endurance Exercise Performance and Metabolism in Female Mice. PMID: ******** DOI: 10.3390/metabo********
Harvey, KL, Holcomb, LE, Kolwicz, SC Jr. Ketogenic diets and exercise performance. Nutrients, 11(10): E2296, 2019. PMID: ******** .
Kolwicz, SC Jr. An "exercise" in cardiac metabolism.  Frontiers in Cardiovascular Medicine, 5:66, 2018.  PMID:  ******** .